Searchable abstracts of presentations at key conferences in endocrinology

ea0029oc4.6 | Pituitary Basic | ICEECE2012

Cell cycle G2/M transition is modulated by microRNAs in pituitary adenomas

Butz H. , Liko I. , Czirjak S. , Korbonits M. , Racz K. , Patocs A.

Background: Although pituitary adenomas are common endocrine neoplasms, the background of their pathogenesis has not clearly revealed. G1/S checkpoint alterations of the cell cycle have already been described in these tumours. MicroRNAs (miRs) which are small, non-coding RNA molecules, and posttranscriptionally regulate protein expression have also identified as potential pathogenic factors in certain cases. Our aim was to determine miR expression profile in pituitary adenomas...